A Lil Bit About Me:
Syima was born in Alor Star, Kedah in 8th of May 1985; where her family was living back then, before they moved to Kulim due to her mother and father’s work. She happily enjoyed her small town life in Kulim until she completed her high school days in Sekolah Menengah Kebangsaan Sultan Badlishah, Kulim in 2002. Then she continued to study Industrial Chemistry (Diploma) in Universiti Teknologi MARA, Perlis (a small state, yet a great place for cheap but yummy delicacies, lots of places to tour in with unique culture blending in and not to mention the chance to cross the border to Thailand!) until she graduated in September 2006. She went to study for bachelor degree in Applied Chemistry in Universiti Teknologi MARA, Shah Alam (the capital of Selangor with attracting shopping malls, near to KL, Klang, pricey food though) until she graduated in November 2008. Currently she’s a M.Sc student under the supervision of Dr. Amin Malik Shah Abdul Majid and her work involves bacterial work in which she is keen to study the expression of IFN – α in E. coli strains. The production of interferons shall be upscaled using our own 3-L biofermentor. The medium to be used will also be replaced with non – animal based medium. Previously during her undergraduates’ days, Syima had experiences of working with HPLC for her final year thesis. Apart from that, she also had experiences of working with AAS, UV-Vis and GC. Syima enjoys gardening around her family house, playing with her cats, playing games, watching movies and listening to music to fill in her free time. Syima is now residing in Seberang Jaya, Pulau Pinang with her family.
Research Interest:
I’m interested in expressing interferon – α using E. coli as the host and cloning the protein so that greater amount of the protein can be produced using a biofermentor. In order to do so, we need to setup the most suitable operating conditions, so that to ensure highest yield and purity of protein can be achieved. The media that will be used in the study will also be replaced with non – animal based media. In this study, interferons is the proteins of interest because interferons generally have the potential of anti – viral, anti – tumor and immunomodulatory activities, which in turn will enables them to be used as therapeutic agents (Nagamine et al, 2009). For these reasons, we are interested in expressing the stated protein, so that if we are capable to produce the product in greater amount, it might have potential to be combined with other kind of drugs to serve as therapeutic agents. We are also interested in optimizing the operating conditions of the biofermentor since it affect cell cultivation performance, and also gene expression. The knowledge of the biofermentor can then be applied in cultivating other types of cells in future.
Syima was born in Alor Star, Kedah in 8th of May 1985; where her family was living back then, before they moved to Kulim due to her mother and father’s work. She happily enjoyed her small town life in Kulim until she completed her high school days in Sekolah Menengah Kebangsaan Sultan Badlishah, Kulim in 2002. Then she continued to study Industrial Chemistry (Diploma) in Universiti Teknologi MARA, Perlis (a small state, yet a great place for cheap but yummy delicacies, lots of places to tour in with unique culture blending in and not to mention the chance to cross the border to Thailand!) until she graduated in September 2006. She went to study for bachelor degree in Applied Chemistry in Universiti Teknologi MARA, Shah Alam (the capital of Selangor with attracting shopping malls, near to KL, Klang, pricey food though) until she graduated in November 2008. Currently she’s a M.Sc student under the supervision of Dr. Amin Malik Shah Abdul Majid and her work involves bacterial work in which she is keen to study the expression of IFN – α in E. coli strains. The production of interferons shall be upscaled using our own 3-L biofermentor. The medium to be used will also be replaced with non – animal based medium. Previously during her undergraduates’ days, Syima had experiences of working with HPLC for her final year thesis. Apart from that, she also had experiences of working with AAS, UV-Vis and GC. Syima enjoys gardening around her family house, playing with her cats, playing games, watching movies and listening to music to fill in her free time. Syima is now residing in Seberang Jaya, Pulau Pinang with her family.
Research Interest:
I’m interested in expressing interferon – α using E. coli as the host and cloning the protein so that greater amount of the protein can be produced using a biofermentor. In order to do so, we need to setup the most suitable operating conditions, so that to ensure highest yield and purity of protein can be achieved. The media that will be used in the study will also be replaced with non – animal based media. In this study, interferons is the proteins of interest because interferons generally have the potential of anti – viral, anti – tumor and immunomodulatory activities, which in turn will enables them to be used as therapeutic agents (Nagamine et al, 2009). For these reasons, we are interested in expressing the stated protein, so that if we are capable to produce the product in greater amount, it might have potential to be combined with other kind of drugs to serve as therapeutic agents. We are also interested in optimizing the operating conditions of the biofermentor since it affect cell cultivation performance, and also gene expression. The knowledge of the biofermentor can then be applied in cultivating other types of cells in future.
