A Lil Bit About Me:
Nozlena Binti Abdul Samad was born on August 8 in Penang , Malaysia.She is the youngest child in a family of three. She happily lived in Bayan Lepas,Penang until finishing her High School.She had her early education at Sungai Ara Primary School and her secondary education (high school) at the Sungai Ara Secondary School.She did her Diploma in Science, Uitm in year 2004, Malaysia and received her BSc (Hons) in Biohealth from UM, Malaysia in year 2007. Currently she is registered to receive her Master degree from Advanced Medical and Dental Institute, USM. The title of her research is “Anti-angiogenic properties of Labisia pumila and its components”. Her research is being supervised by Dr Gurjeet Kaur a/p Chatar Singh (AMDI), Dr Amin Malik Shah Abd Majid (School of Pharmaceutical Sciences) and Dr Tan Mei Lan (AMDI ), Universiti Sains Malaysia. Her research area is in molecular pharmacology. Topics of M.Sc , posters and as well as her oral presentation , reflect her work and involvement in various techniques and machine handling such as angiogenesis , basic cell culture, media preparation, culturing techniques , cell maintenance, cytotoxicity , apoptosis and spectroscopy machine (Fourier Transform Infrared Spectroscopy,Gas Chromatography-Mass Spectroscopy). She was a recipient of the Academic Staff Training Scheme (ASTS) Scholarship.
Research Interest:
Cancer develops when cells in a part of the body begin to grow out of control. For the past decades, several studies were done in order to cure cancer. These studies have given to the market several drugs and therapies. Radiotherapy and surgery are somewhat expensive and it can only be used in the removal of local tumours, not metastatic cancer. I am interested in natural products that have the potential to be used as an anti tumor agent. Since the approval of the antiangiogenic agent Avastin( bevacizumab, rhuMAb-VEF) for the treatment of metastatic breast and colorectal cancer, the interest in agents that can inhibit tumor vasculature development grew significantly. Studies have shown that leaf extracts of Labisia pumila has potent anti-oxidative properties as shown by its xantine oxidase inhibitory ability.Antioxidants are well known for their antitumor properties with inhibition of tumor vasculature development (angiogenesis) being one of the primary routes. This encouraged me to test this plant for its anti-angiogenic activity using the rat aorta model, characterize the molecular pathway(s) perturbed and assess any synergistic activity of Labisia pumila with Tamoxifen for the treatment of breast cancer.
Poster Presentation:
Poster participation in MSPP Scientific MeetingPlace: University of Malaya , Kuala Lumpur , Malaysia
Date: 5th-6th April
Poster title: Kacip fatimah ( Labisia Pumila ) and Its Role in Tumor Development Inhibition.Nozlena A Samad , Hayder B. Sahib , Ng Kok Wen , Zhari Ismail , Gurjeet Kaur ,Amin M. S. A. Majid.
Poster participation in 2nd USM Penang International Postgraduate Convention 2008
Place: University Science Malaysia
Date: 18th-20th June 2008
Poster title: Effects of Methanol Extract of Ficus deltoidea on Human Liver Cancer
Nozlena A. Samad , Hayder B. Sahib , Zunoliza Abdullah , Zhari Ismail , Gurjeet Kaur,
Amin M. S. A. Majid
- 4th Asian Association of Schools of Pharmacy -9th Malaysian Pharmaceutical Society Pharmacy Scientific Conference 2009
10-13 June, 2009
Universiti Sains Malaysia, Penang, Malaysia
Title: Anti-Angiogenic Properties Of Labisia Pumila Leaves Extract
